Progress in proteomics-based diagnosis of hepatocellular carcinoma

Hepatocellular Carcinoma in Sheep

Proteomics of hepatocellular carcinoma in Chinese patients.

Hepatocellular carcinoma (HCC) is a malignant tumor of liver that causes approximately half a million deaths each year, of which over half of the cases are diagnosed in China. Because of its asymptomatic nature, HCC is usually diagnosed at late and advanced stages, for which there are no effective therapies. Thus, biomarkers for early detection and molecular targets for treating HCC are urgentl...

Evaluation of serum AFP (α-fetoprotein) level in HBsAg carrier patients for diagnosis of hepatocellular carcinoma

Background: Hepatocellular carcinoma (HCC) is common all over the world as well as Iran. The incidence of HCC is higher in hepatitis B carriers and it is highly recommended to periodically screen these patients by serum alpha-fetoprotein (AFP) and liver ultrasound (US) every 6 months. We explore the diagnostic accuracy and the performance of (AFP) in cases of hepatitis B carriers as a scree...

Hepatocellular carcinoma in a sheep

At necropsy of a five-year-old sheep, a pear shaped, lobular yellow-brownish mass measuring about 12 ×15 × 20 cm was found to involve the right hepatic lobe. Microscopic examination revealed two trabecularand solid patterns of neoplastic hepatocytes. In solid pattern, there were numerous tumoral giant cells thatcontain one or more large hyperchromatic bizarre-shaped nuclei scattered among clust...

diagnosis and staging of hepatocellular carcinoma

hepatocellular carcinoma (hcc) is the fifth most common tumor in the world, and its incidence is increasing. it is second most common cause of cancer related death worldwide and fastest growing cause of cancer death in the united states. cirrhosis is the most important clinical risk factor for hcc, with approximately 80% of cases of hcc developing in patients with a cirrhotic liver. hcc differs...